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1

Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)

Wang, Jiang, Sánchez-Roselló, María, Aceña, José Luis, del Pozo, Carlos, Sorochinsky, Alexander E., Fustero, Santos, Soloshonok, Vadim A., Liu, Hong

Journal:

Chemical Reviews

Year:

2014

Language:

english

File:

PDF, 11.00 MB

english, 2014

2

[ACS Symposium Series] Fluorine-Containing Synthons Volume 911 || SF 5 -Synthons: Pathways to Organic Derivatives of SF 6

Soloshonok, Vadim A.

Year:

2005

Language:

english

File:

PDF, 3.72 MB

english, 2005

3

Fluorine‐Containing Drugs Approved by the FDA in 2018

Mei, Haibo, Han, Jianlin, Fustero, Santos, Medio-Simon, Mercedes, Sedgwick, Daniel M., Santi, Claudio, Ruzziconi, Renzo, Soloshonok, Vadim Anatolievich

Journal:

Chemistry - A European Journal

Year:

2019

Language:

english

File:

PDF, 3.70 MB

english, 2019

4

[ACS Symposium Series] Fluorine-Containing Synthons Volume 911 || Regioexhaustive Functionalizations: To Miss an Isomer Means to Miss a Chance

Soloshonok, Vadim A.

Year:

2005

Language:

english

File:

PDF, 1.52 MB

english, 2005

5

Chiral sulfoxides: advances in asymmetric synthesis and problems with the accurate determination of the stereochemical outcome

Han, Jianlin, Soloshonok, Vadim A., Klika, Karel D., Drabowicz, Józef, Wzorek, Alicja

Journal:

Chemical Society Reviews

Year:

2018

Language:

english

File:

PDF, 3.14 MB

english, 2018

6

Synthesis of fluorine-containing compounds under operationally convenient conditions

Vadim A. Soloshonok, Dmitrii O. Berbasov

Journal:

Journal of Fluorine Chemistry

Year:

2004

Language:

english

File:

PDF, 174 KB

english, 2004

7

Synthesis of Trifluoromethyl-Containing Vicinal Diamines by Asymmetric Decarboxylative Mannich Addition Reactions

Wu, Lingmin, Xie, Chen, Mei, Haibo, Dai, Yanling, Han, Jianlin, Soloshonok, Vadim A., Pan, Yi

Journal:

Journal of Organic Chemistry

Year:

2015

Language:

english

File:

PDF, 595 KB

english, 2015

8

Ni-catalyzed asymmetric decarboxylative Mannich reaction for the synthesis of β-trifluoromethyl-β-amino ketones

Qian, Ping, Dai, Yanling, Mei, Haibo, Soloshonok, Vadim A., Han, Jianlin, Pan, Yi

Journal:

Year:

2015

Language:

english

File:

PDF, 914 KB

english, 2015

9

Modern Approaches for Asymmetric Construction of Carbon–Fluorine Quaternary Stereogenic Centers: Synthetic Challenges and Pharmaceutical Needs

Zhu, Yi, Han, Jianlin, Wang, Jiandong, Shibata, Norio, Sodeoka, Mikiko, Soloshonok, Vadim A., Coelho, Jaime A. S., Toste, F. Dean

Journal:

Chemical Reviews

Year:

2018

Language:

english

File:

PDF, 27.58 MB

english, 2018

10

Operationally convenient asymmetric synthesis of (S)- and (R)-3-amino-4,4,4-trifluorobutanoic acid: Part II. Enantioselective biomimetic transamination of 4,4,4-trifluoro-3-oxo-N-[(R)-1-phenylethyl]butanamide

Vadim A. Soloshonok, Hironari Ohkura, Manabu Yasumoto

Journal:

Journal of Fluorine Chemistry

Year:

2006

Language:

english

File:

PDF, 274 KB

english, 2006

11

ChemInform Abstract: β-Fluorosubstituted Amino Acids

KUKHAR', V. P., YAGUPOL'SKII, YU. L., SOLOSHONOK, V. A.

Journal:

Year:

1990

File:

PDF, 85 KB

1990

12

Electrochemical fluorination of 1-ethylpiperazine and 4-methyl- and/or 4-ethylpiperazinyl substituted carboxylic acid methyl esters

Takashi Abe, Hajime Baba, Irina Soloshonok

Journal:

Journal of Fluorine Chemistry

Year:

2001

Language:

english

File:

PDF, 332 KB

english, 2001

13

Stereoselective Additions of α-Lithiated Alkyl- p -tolylsulfoxides to N -PMP(fluoroalkyl)aldimines. An Efficient Approach to Enantiomerically Pure Fluoro Amino Compounds

Bravo, Pierfrancesco, Farina, Alessandra, Kukhar, Valery P., Markovsky, Andrey L., Meille, Stefano V., Soloshonok, Vadim A., Sorochinsky, Alexander E., Viani, Fiorenza, Zanda, Matteo, Zappalà, Carmela

Journal:

Journal of Organic Chemistry

Year:

1997

Language:

english

File:

PDF, 71 KB

english, 1997

14

Electrochemical fluorination of (N,N-dialkylamino)alcohols

Takashi Abe, Haruhiko Fukaya, Eiji Hayashi, Taizo Ono, Masakazu Nishida, Irina Soloshonok, Kunio Okuhara

Journal:

Journal of Fluorine Chemistry

Year:

1999

Language:

english

File:

PDF, 237 KB

english, 1999

15

Biocatalytic resolution of β-fluoroalkyl-β-amino acids

Vadim A. Soloshonok, Alexander G. Kirilenko, Nataly A. Fokina, Irine P. Shishkina, Sergey V. Galushko, Valery P. Kukhar, Vytas K. Švedas, Elena V. Kozlova

Journal:

Tetrahedron: Asymmetry

Year:

1994

Language:

english

File:

PDF, 612 KB

english, 1994

16

[ACS Symposium Series] Current Fluoroorganic Chemistry Volume 949 (New Synthetic Directions, Technologies, Materials, and Biological Applications) || Cationic Cyclizations of Fluoro Alkenes: Fluorine as a Controller and an Activator

Soloshonok, Vadim A., Mikami, Koichi, Yamazaki, Takashi, Welch, John T., Honek, John F.

Year:

2007

Language:

english

File:

PDF, 1.03 MB

english, 2007

17

General asymmetric synthesis of 2,2,2-trifluoro-1-(1H-indol-3- and -2-yl)ethanamines

Wu, Lingmin, Xie, Chen, Zhou, Jie, Mei, Haibo, Soloshonok, Vadim A., Han, Jianlin, Pan, Yi

Journal:

Journal of Fluorine Chemistry

Year:

2015

Language:

english

File:

PDF, 424 KB

english, 2015

18

Aliphatic fluorine-containing amino acids

V. P. Kukhar', V. A. Soloshonok

Year:

1991

Language:

english

File:

PDF, 1.52 MB

english, 1991

19

[ACS Symposium Series] Fluorine-Containing Synthons Volume 911 || A New Aspect of Fluoroalkylated Acetylenes: Synthesis and Applications—Hydrometallation and Carbometallation

Soloshonok, Vadim A.

Year:

2005

Language:

english

File:

PDF, 1.49 MB

english, 2005

20

[ACS Symposium Series] Fluorine-Containing Synthons Volume 911 || Haloperfluorocarbons: Versatile Tectons in Halogen Bonding Based Crystal Engineering

Soloshonok, Vadim A.

Year:

2005

Language:

english

File:

PDF, 3.38 MB

english, 2005

21

Asymmetric Friedel–Crafts Reactions of N - tert -Butylsulfinyl-3,3,3-trifluoroacetaldimines: General Access to Enantiomerically Pure Indoles Containing a 1-Amino-2,2,2-trifluoroethyl Group

Wu, Lingmin, Xie, Chen, Mei, Haibo, Soloshonok, Vadim A., Han, Jianlin, Pan, Yi

Journal:

Journal of Organic Chemistry

Year:

2014

Language:

english

File:

PDF, 645 KB

english, 2014

22

Operationally convenient method for preparation of sulfonamides containing α,α-difluoro-β-amino carbonyl moiety

Xie, Chen, Wu, Lingmin, Mei, Haibo, Soloshonok, Vadim A., Han, Jianlin, Pan, Yi

Journal:

Tetrahedron Letters

Year:

2014

Language:

english

File:

PDF, 580 KB

english, 2014

23

Recent advances in the trifluoromethylation methodology and new CF3-containing drugs

Zhu, Wei, Wang, Jiang, Wang, Shuni, Gu, Zhanni, Aceña, José Luis, Izawa, Kunisuke, Liu, Hong, Soloshonok, Vadim A.

Journal:

Journal of Fluorine Chemistry

Year:

2014

Language:

english

File:

PDF, 1.43 MB

english, 2014

24

Recent Advances in the Asymmetric Synthesis of α-(Trifluoromethyl)-Containing α-Amino Acids

Aceña, José, Sorochinsky, Alexander, Soloshonok, Vadim

Journal:

Year:

2012

Language:

english

File:

PDF, 314 KB

english, 2012

25

Electrochemical fluorination of di- and tri-(2-hydroxyethyl)-substituted alkylamines

Takashi Abe, Irina Soloshonok, Hajime Baba, Akira Sekiya

Journal:

Journal of Fluorine Chemistry

Year:

1999

Language:

english

File:

PDF, 182 KB

english, 1999

26

[ACS Symposium Series] Fluorine-Containing Synthons Volume 911 || Recent Advances in Perfluoroalkylation Methodology

Soloshonok, Vadim A.

Year:

2005

Language:

english

File:

PDF, 1.66 MB

english, 2005

27

Optical Purifications via Self-Disproportionation of Enantiomers by Achiral Chromatography: Case Study of a Series of α-CF 3 -containing Secondary Alcohols

Sorochinsky, Alexander E., Katagiri, Toshimasa, Ono, Taizo, Wzorek, Alicja, Aceña, José Luis, Soloshonok, Vadim A.

Journal:

Year:

2013

Language:

english

File:

PDF, 119 KB

english, 2013

28

Biocatalytic approach to enantiomerically pure β-amino acids

Vadim A. Soloshonok, Nataly A. Fokina, Antonyna V. Rybakova, Irine P. Shishkina, Sergey V. Galushko, Alexander E. Sorochinsky, Valery P. Kukhar, Mariya V. Savchenko, Vytas K. Švedas

Journal:

Tetrahedron: Asymmetry

Year:

1995

Language:

english

File:

PDF, 666 KB

english, 1995

29

Asymmetric synthesis of α-amino acids via homologation of Ni(II) complexes of glycine Schiff bases. Part 2: Aldol, Mannich addition reactions, deracemization and (S) to (R) interconversion of α-amino acids

Sorochinsky, Alexander E., AceÃ±a, JosÃ© Luis, Moriwaki, Hiroki, Sato, Tatsunori, Soloshonok, Vadim

Journal:

Year:

2013

Language:

english

File:

PDF, 995 KB

english, 2013

30

Synthesis of (2S,3S)-β-(trifluoromethyl)-α,β-diamino acid by Mannich addition of glycine Schiff base Ni(II) complexes to N-tert-butylsulfinyl-3,3,3-trifluoroacetaldimine

Kawamura, Akie, Moriwaki, Hiroki, Röschenthaler, Gerd-Volker, Kawada, Kosuke, Aceña, José Luis, Soloshonok, Vadim A.

Journal:

Journal of Fluorine Chemistry

Year:

2015

Language:

english

File:

PDF, 448 KB

english, 2015

31

[ACS Symposium Series] Current Fluoroorganic Chemistry Volume 949 (New Synthetic Directions, Technologies, Materials, and Biological Applications) || Stereoselective Synthesis of Polyfluorinated Exo -Tricyclononenes and Norbornenes

Soloshonok, Vadim A., Mikami, Koichi, Yamazaki, Takashi, Welch, John T., Honek, John F.

Year:

2007

Language:

english

File:

PDF, 1.80 MB

english, 2007

32

[ACS Symposium Series] Fluorine-Containing Synthons Volume 911 || Fluoroform, Fluoral, Trifluoroacetic, and Trifluoromethanesulfinic Acids Derivatives as New Reagents for the Introduction of Polyfluorinated Moieties

Soloshonok, Vadim A.

Year:

2005

Language:

english

File:

PDF, 3.06 MB

english, 2005

33

[ACS Symposium Series] Fluorine-Containing Synthons Volume 911 || New Nucleophilic Fluoroalkylation Chemistry

Soloshonok, Vadim A.

Year:

2005

Language:

english

File:

PDF, 3.90 MB

english, 2005

34

Generalized Approach to Asymmetric Synthesis of β-Substituted β-Amino Acids Bearing CHF 2 , CBrF 2 , and CClF 2 Groups

Dai, Yanling, Xie, Chen, Zhou, Jie, Mei, Haibo, Soloshonok, Vadim A., Han, Jianlin, Pan, Yi

Journal:

Asian Journal of Organic Chemistry

Year:

2015

Language:

english

File:

PDF, 484 KB

english, 2015

35

Biomimetic Reductive Amination of Fluoro Aldehydes and Ketones via [1,3]-Proton Shift Reaction.1 Scope and Limitations

Ono, Taizo, Kukhar, Valery P., Soloshonok, Vadim A.

Journal:

Journal of Organic Chemistry

Year:

1996

Language:

english

File:

PDF, 323 KB

english, 1996

36

[ACS Symposium Series] Current Fluoroorganic Chemistry Volume 949 (New Synthetic Directions, Technologies, Materials, and Biological Applications) || Synthesis of Novel gem -Difluorinatedcyclopropane Hybrids: Applications for Material and Medicinal Sciences

Soloshonok, Vadim A., Mikami, Koichi, Yamazaki, Takashi, Welch, John T., Honek, John F.

Year:

2007

Language:

english

File:

PDF, 983 KB

english, 2007

37

Perfluoro-3-ethyl-2,4-dimethyl-3-pentyl persistent radical: A new reagent for direct, metal-free radical trifluoromethylation and polymer initiation

Mei, Haibo, Han, Jianlin, White, Sarah, Butler, Greg, Soloshonok, Vadim A.

Journal:

Journal of Fluorine Chemistry

Year:

2019

Language:

english

File:

PDF, 5.31 MB

english, 2019

38

Fluorine chemistry in Ukraine

Yurii L. Yagupolskii, Vadim A. Soloshonok

Journal:

Journal of Fluorine Chemistry

Year:

2010

Language:

english

File:

PDF, 116 KB

english, 2010

39

Generalized access to fluorinated β-keto amino compounds through asymmetric additions of α,α-difluoroenolates to CF 3 -sulfinylimine

Xie, Chen, Wu, Lingmin, Mei, Haibo, Soloshonok, Vadim A., Han, Jianlin, Pan, Yi

Journal:

Organic & Biomolecular Chemistry

Year:

2014

Language:

english

File:

PDF, 317 KB

english, 2014

40

Asymmetric synthesis of quaternary α-fluoro-β-keto-amines via detrifluoroacetylative Mannich reactions

Xie, Chen, Dai, Yanling, Mei, Haibo, Han, Jianlin, Soloshonok, Vadim A., Pan, Yi

Journal:

Chemical Communications

Year:

2015

Language:

english

File:

PDF, 767 KB

english, 2015

41

Self-Disproportionation of Enantiomers (SDE) via achiral gravity-driven column chromatography of N-fluoroacyl-1-phenylethylamines

Wzorek, Alicja, Kamizela, Angelika, Sato, Azusa, Soloshonok, Vadim A.

Journal:

Journal of Fluorine Chemistry

Year:

2016

Language:

english

File:

PDF, 862 KB

english, 2016

42

New asymmetric approach to β-trifluoromethyl isoserines

Shevchuk, Michael V., Kukhar, Valery P., Röschenthaler, Gerd-Volker, Bassil, Bassem S., Kawada, Kosuke, Soloshonok, Vadim A., Sorochinsky, Alexander E.

Journal:

Year:

2013

Language:

english

File:

PDF, 398 KB

english, 2013

43

Practical Methods for the Synthesis of Symmetrically α,α-Disubstituted α-Amino Acids

Soloshonok, Vadim, Sorochinsky, Alexander

Journal:

Year:

2010

Language:

english

File:

PDF, 492 KB

english, 2010

44

Asymmetric Synthesis of Organoelement Analogues of Natural Products; Part 12: General Method for the Asymmetric Synthesis of Fluorine-Containing Phenylalanines and α-Methyl(phenyl)alanines via Alkylation of the Chiral Nickel(II) Schiff's Base Complexes of Glycine and Alanine

Kukhar, Valeri P., Belokon, Yuri N., Soloshonok, Vadim A., Svistunova, Nataly Yu., Rozhenko, Alexander B., Kuz'mina, Nadezhda A.

Journal:

Year:

1993

File:

PDF, 327 KB

1993

45

Detrifluoroacetylative generation and chemistry of fluorine containing tertiary enolates

Zhang, Lijun, Zhang, Wenzhong, Sha, Wanxing, Mei, Haibo, Han, Jianlin, Soloshonok, Vadim A.

Journal:

Journal of Fluorine Chemistry

Year:

2016

Language:

english

File:

PDF, 1.05 MB

english, 2016

46

Synthesis of highly 1,3-proton shift transferable N-benzyl imines of trifluoroacetophenone under the “low-basicity” reaction conditions

Dmitrii O Berbasov, Ifeyinwa D Ojemaye, Vadim A Soloshonok

Journal:

Journal of Fluorine Chemistry

Year:

2004

Language:

english

File:

PDF, 107 KB

english, 2004

47

2,2,2-Trifluoro-1-(1-adamantyl)ethylamine hydrochloride

A.G. Yurchenko, T.V. Fedorenko, V.P. Tikchonov, V.A. Soloshonok, V.P. Kukhar'

Journal:

Journal of Fluorine Chemistry

Year:

1992

Language:

english

File:

PDF, 302 KB

english, 1992

48

[ACS Symposium Series] Fluorine-Containing Synthons Volume 911 || Asymmetric Synthesis of Monofluorinated Compounds Having the Fluorine Atom Vicinal to π-Systems

Soloshonok, Vadim A.

Year:

2005

Language:

english

File:

PDF, 1.56 MB

english, 2005

49

[ACS Symposium Series] Current Fluoroorganic Chemistry Volume 949 (New Synthetic Directions, Technologies, Materials, and Biological Applications) || An Issue of Synthesis Strategy: To Make or Rather to Transform Organofluorine Compounds

Soloshonok, Vadim A., Mikami, Koichi, Yamazaki, Takashi, Welch, John T., Honek, John F.

Year:

2007

Language:

english

File:

PDF, 1.21 MB

english, 2007

50

ChemInform Abstract: Phenyl-α,α,ω-trihydropolyfluoroalkyliodonium Borofluorides.

MIRONOVA, A. A., SOLOSHONOK, I. V., MALETINA, I. I., ORDA, V. V., YAGUPOL'SKII, L. M.

Journal:

Year:

1988

File:

PDF, 206 KB

1988

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